Investigating the Correlation between Changes in the Severity of Obstructive Sleep Apnea and Changes in Patient's Quality of Life Using SAQLI.
Abstract: Background: The purpose of this study was to investigate whether reduction in AHI by 50%, which is used as an indicator of improvement in obstructive sleep apnea, would result in an improved quality of life for patients using oral appliances for the treatment of obstructive sleep apnea. Materials and methods: Thirty-two (32) subjects were recruited from the Dental sleep Medicine Clinic, ... read moreTufts University School of Dental Medicine. Data were collected at baseline (pretreatment) and at a second, post-treatment visit following a minimum of 4 weeks of intervention. Data for the SAQLI questionnaire were collected using an Audio Computer-Assisted Self Interviewing survey system and via in-person interviews. Pre- and post-mean AHI scores and SAQLI scores were compared using a paired-sample t-test. The association between the change in SAQLI scores and in AHI between pre- and post-treatment were determined using Pearson correlation analysis, as the data were distributed normally. A p-value <0.05 was considered statistically significant. Results: A total of 32 subjects were recruited for the study, 18 females and 14 males, with an average age of 53.88 (SD=12.36) years. 87.5% of the subject population was White, 3.1% was African and Hispanic subjects, and 6.3% was Asian. Twenty-five (25) subjects, 13 females and 12 males, completed the SAQLI questionnaire and were included in the analysis. A paired t- test was conducted and showed significant results in AHI values (p = 0.02), while the SAQLI scores were not significant (p = 0.14). OSA affected negatively all four domains of SAQLI however; Social interaction and symptoms showed most improvement among others. No significant correlation was found between the severity of obstructive sleep apnea using AHI and SAQLI scores (p = 0.106). Conclusions: Following treatment, the quality of life of patients with OSA showed lack of improvement as measured by SAQLI however; social interaction and symptoms domains displayed marked improvement. AHI values after intervention showed important changes; however, the change in severity of AHI was not correlated with the change in severity of SAQLI scores. Keywords: Sleep apnea, Quality of life, sleep apnea quality of life, SAQLI, apnea-hypopnea index, AHI
Thesis (M.S.)--Tufts University, 2016.
Submitted to the Dept. of Other.
Advisor: Leopoldo Correa.
Committee: Noshir Mehta, Ronald Kulich, Tofool Alghanem, and George Maloney.
Keyword: Dentistry.read less