Molecular and Pharmacological Analysis of the Chemokine Receptor CCR6

Julian, Bina.


  • Abstract: This thesis advances the molecular understanding of Cys-Cys Chemokine Receptor 6 (CCR6) through mutagenesis studies and the development of CCR6-based tools that measure and modulate receptor function. CCR6 is a G protein-coupled receptor (GPCR) whose signaling influences the behavior of a wide range of cells involved in the inflammatory response. CCR6 has gained attention for its express... read more
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