Shedding light on the role for astrocytic D-serine on NMDAR activation

Dunphy, Jaclyn.


  • Astrocytes release signaling molecules at synapses in a process known as gliotransmission, but how this impacts synaptic physiology over time is unclear. In this report we explore the impact of gliotransmission on synaptic activity by attenuating vesicular release with both molecular genetic and optogenetic approaches. First we show that astrocytes release D-serine in a wakefulness-dependent ... read more
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