Characterization of a novel population of T-follocular helper cells in health and disease.

Adkins, Elisabeth.


  • Abstract: T-follicular helper cells (TFH) are critical for efficient humoral immunity and contribute to the development of autoimmune diseases. TFH cells develop from a nave CD4+ T cell after DC priming and transitions through a precursor-TFH (pre-TFH) stage that is distinguished by cell surface expression of CXCR5. The pre-TFH cell then transitions to full-TFH after encountering its cognate B cel... read more
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