Turning Cold Tumors Hot: Exploring Whether Val-boroPro and Val-boroPro and Doxorubicin Exhibit Synergy in the CT-26 Mouse Tumor Model.

Margosian, Victoria.


  • Val-boroPro, a compound first synthesized in the Bachovchin Lab at Tufts University Sackler School of Graduate Biomedical Sciences as a dipeptidyl aminopeptidase inhibitor, was found to stimulate the production of specific cytokines that enhance the immune response to tumors in a variety of mouse models. However, in these models, a criteria observed to mediate Val-boroPro's efficacy was the ... read more
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