FUBP1 as a Long Tail Driver and Widespread Regulator of Tumor Suppressor Gene Alternative Splicing

Elman, Jessica.


  • Comprehensive sequencing approaches have allowed for the identification of the most frequent contributors to cancer, known as drivers. These approaches have also revealed a class of somatic mutations in understudied, infrequently altered genes, referred to as "long tail" (LT) drivers. A key challenge has been to find clinically relevant LT drivers and understand how they cooperate to drive ... read more
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