Detangling PPI Networks to Uncover Functionally Meaningful Clusters.

Hall-Swan, Sarah.

2018

Description
  • We compare computational methods for decomposing a PPI network into non-overlapping modules. A method is preferred if it results in a large proportion of nodes being assigned to functionally meaningful modules, as measured by functional enrichment over terms from the Gene Ontology (GO). We compare the performance of three popular community detection algorithms that produce non-overlapping clusters... read more
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