Insights into the Mechanism of Oxygen-mediated Growth Arrest of Bacteroides fragilis.

Meehan, Brian.


  • Abstract: The goal of this work was to define the factors that inhibit growth of Bacteroides fragilisat oxygen levels > 0.05%. One important aspect of this growth arrest is the accumulation of endogenously-generated reactive oxygen species (ROS) like hydrogen peroxide (H2O2). We show here that H2O2 scavenging rates were reduced to 20% of the wild-type in a strain missing alkylhydroperoxide redu... read more
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