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This thesis investigates the cross-body signaling phenomenon that occurs in response to amputation in regenerating Xenopus froglets. In response to amputation, the contralateral, unharmed limb becomes depolarized. This depolarization event is an extremely fast, amputation specific, and mirrored response to what occurs in the affected limb, and only occurs in regenerating froglets. This thesis seeks ... read moreto characterize bioelectric injury mirroring (BIM), and provide insight into its possible mechanisms and function in limb regeneration.read less
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