The Role of APOBECs in R-Loop Associated Chromosomal Fragility and Instability at CAG Repeats in S. cerevisiae

Larsen, Benjamin B.

2021

Description
  • My project explored whether human cytosine deaminase enzymes of the APOBEC family are capable of inducing chromosomal fragility and instability at CAG repeat regions in an R-loop dependent manner using baker's yeast as a model organism.

    Advisor: Dr. Catherine Freudenreich
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