Purification of Human SIRT4 in Escherichia coli.

Park, Albert.

2017

Description
  • The sirtuins (SIRT1–7) comprise a conserved class of NAD-dependent enzymes involved in metabolic regulation and cell survival. Their dependence on NAD inherently renders the sirtuins sensors of energy and thus offers a mechanistic link among energy availability, metabolism, and cell survival. Of the mitochondrial sirtuins, SIRT4 is the least biochemically understood sirtuin. Although ADP-ribosyltr... read more
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5999nf679
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