Transcriptome analysis of pig intestinal cell monolayers infected with Cryptosporidium parvum asexual stages.

Mirhashemi, Marzieh Ezzaty.

Noubary, Farzad.

Chapman-Bonofiglio, Susan.

Tzipori, Saul.

Huggins, Gordon S.

Widmer, Giovanni.


  • Background: Human cryptosporidiosis is caused primarily by two species of apicomplexan protozoa, Cryptosporidium parvum and C. hominis. In cultured cell monolayers, the parasite undergoes two generations of asexual multiplication (merogony). However, the proportion of parasites completing the life-cycle is low and insufficient to sustain continuous propagation. Due to the intracellular location of ... read more
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