| Description |
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Introduction: Obesity, which is excessive expansion of white adipose
tissue, is a major risk factor for several serious health issues, including diabetes,
cardiovascular disease and cancer. Efforts to combat obesity and related diseases
require understanding the basic biology of adipogenesis. However, in vitro studies do
not result in ... read morelipid composition and morphology that are typically seen in vivo,
likely because the in vitro conditions are not truly representative of in vivo
adipose tissue formation. In vitro, low oxygen tension and cytoskeletal tension have
been shown to independently regulate adipogenesis, but in vivo, these two factors
simultaneously influence differentiation.
Keywords: Adipogenesis, Cytoskeleton, Oxygen tension, Adipose-derived
stem cells.
Springer Open.read less
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This object is in collection
| Citation |
- Schiller, Zachary, Nathan R. Schiele, James K. Sims, Kyongbum
Lee, and Catherine K. Kuo. "Adipogenesis of adipose-derived stem cells may be
regulated via the cytoskeleton at physiological oxygen levels in vitro." Stem Cell
Research & Therapy 4, no. 6 (12, 2013): 1-10.
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