Designing Adenoviral Vectors for Gene Therapy.

Swegiard, John.


  • Abstract: The eye represents an isolated and immune privileged region of the body where multiple gene polymorphisms have been identified. Therefore, gene therapy is an attractive therapeutic approach to ameliorate disease. Adenovirus has been used successfully in multiple clinical trials, has a large cloning capacity, does not integrate into genomic DNA, and is capable of expressing for long perio... read more
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