Background: Stoichiometric models provide a structural framework for
analyzing steady-state cellular behavior. Models are developed either through
augmentations of existing models or more recently through automatic reconstruction
tools. There is currently no standardized practice or method for validating the
properties of a model before ... read moreplacing it in the public domain. Considerable effort is
often required to understand a model's inconsistencies before its reuse within new
Keywords: Constraint-based modeling, Pathway analysis, Model validation,
Consistency checking, Model reuse.