Metabolic flux analysis of mitochondrial uncoupling in 3T3-L1 adipocytes.

Si, Yaguang.

Shi, Hai.

Lee, Kyongbum.


  • Background: Increasing energy expenditure at the cellular level offers an attractive option to limit adiposity and improve whole body energy balance. In vivo and in vitro observations have correlated mitochondrial uncoupling protein-1 (UCP1) expression with reduced white adipose tissue triglyceride (TG) content. The metabolic basis for this correlation remains unclear. Methodology/Principal Findings: ... read more
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  • Si Y, Shi H, Lee K (2009) Metabolic Flux Analysis of Mitochondrial Uncoupling in 3T3-L1 Adipocytes. PLoS ONE 4(9): e7000. doi:10.1371/journal.pone.0007000.
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