Background: The reliability of estimating muscle fiber cross-sectional
area (measure of muscle fiber size) and fiber number from only a subset of fibers in
rat hindlimb muscle cross-sections has not been systematically evaluated. This study
examined the variability in mean estimates of fiber cross-sectional area as a
function of the number ... read moreof fibers measured, and tested whether counting a subset of
fibers in a cross-section could predict total fiber number in middle-aged
rats.
Ceglia, Lisa, Sathit Niramitmahapanya, Lori L. Price, Susan S.
Harris, Roger A. Fielding, and Bess Dawson-Hughes. "An evaluation of the reliability
of muscle fiber cross-sectional area and fiber number measurements in rat skeletal
muscle." Biological Procedures Online 15, no. 1 (12, 2013):
1-6.