Using 3D Models to Investigate the Impaired Wound Healing Functions of Diabetic Foot Ulcer-Derived Fibroblasts.

Maione, Anna.


  • Abstract: Diabetic foot ulcers (DFU) are a serious and debilitating complication of diabetes. Unfortunately, many DFUs are refractory to current treatments and result in amputation. In order to develop more effective therapies, we must better understand how cellular dysfunctions mediate the pathobiology of chronic wounds. However, conventional monolayer cultures and in vivo wound models have been ... read more
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