Understanding molecular mechanisms of homeostasis: The role of the Vacuolar H+-ATPase in amino acid sensing

Stransky, Laura.

2017

Description
  • Abstract: Cells continuously sense and respond to environmental conditions to maintain homeostasis. The signaling underling this ability is complex and incompletely understood, particularly with respect to how amino acids are sensed. Vacuolar-type H+-ATPase (V‑ATPase) function is required for amino acid-dependent activation of mTORC1, a critical node of cellular homeostasis and amino acid sens... read more
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