Description |
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Background: Tissue fibrosis is an integral component of chronic
inflammatory (liver and pancreas) diseases and pancreatic cancer. Activated
pancreatic- (PSC) and hepatic- (HSC) stellate cells play a key role in fibrogenesis.
To identify organ- and disease-specific stellate cell transcriptional fingerprints,
we employed genome-wide ... read moretranscriptional analysis of primary human PSC and HSC
isolated from patients with chronic inflammation or cancer.
Keywords: Chronic pancreatitis, Hepatic stellate cells,
Immunohistochemistry, Liver cirrhosis, Liver metastasis, Pancreatic ductal
adenocarcinoma, Pancreatic stellate cells.
Springer Open.read less
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Citation |
- Erkan, Mert, Nadine Weis, Zheng Pan, Christian Schwager, Tamar
Samkharadze, Xiaohua Jiang, Ute Wirkner, Nathalia A. Giese, Wilhelm Ansorge, Jürgen
Debus, Peter E. Huber, Helmut Friess, Amir Abdollahi, and Jörg Kleeff. "Organ-,
inflammation- and cancer specific transcriptional fingerprints of pancreatic and
hepatic stellate cells." Molecular Cancer 9, no. 1 (12, 2010):
1-15.
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