Investigating the Genetic Interactions of PAX8, a Lineage-Specific Transcription Factor in Ovarian Cancer

Assaad, Jonathan R.


  • Ovarian cancer has the highest mortality rate of all female cancers and an even higher recurrence rate of 85%. Current treatment methods including platinum-based chemotherapy and PARP inhibitors have significantly improved the overall cancer prognosis, but still struggle to overcome the obstacles of resistance, recurrence, and off-targeting. Development of new ovarian cancer treatment is in an area ... read more
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