| Description |
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Background: Coronaviruses are an important cause of infectious diseases
in humans, including severe acute respiratory syndrome (SARS), and have the continued
potential for emergence from animal species. A major factor in the host range of a
coronavirus is its receptor utilization on host cells. In many cases,
coronavirus-receptor interactions ... read moreare well understood. However, a notable exception
is the receptor utilization by group 3 coronaviruses, including avian infectious
bronchitis virus (IBV). Feline aminopeptidase N (fAPN) serves as a functional
receptor for most group 1 coronaviruses including feline infectious peritonitis virus
(FIPV), canine coronavirus, transmissible gastroenteritis virus (TGEV), and human
coronavirus 229E (HCoV-229E). A recent report has also suggested a role for fAPN
during IBV entry (Miguel B, Pharr GT, Wang C: The role of feline aminopeptidase N as
a receptor for infectious bronchitis virus. Brief review. Arch Virol 2002,
147:2047-2056.
Springer Open.read less
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This object is in collection
| Citation |
- Chu, Victor, Lisa J. McElroy, Jed M. Aronson, Trisha J. Oura,
Carole E. Harbison, Beverley E. Bauman, and Gary R. Whittaker. "Feline aminopeptidase
N is not a functional receptor for avian infectious bronchitis virus." Virology
Journal 4, no. 1 (12, 2007): 1-10.
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