CCN5 as an In Vivo Inhibitor of Leiomyoma Formation.

Russo, Joshua.


  • Abstract: Uterine leiomyoma is the most prevalent of all tumors in women. It has a clinical incidence in the general population over 25%, and the incidence in women of African descent is >80%. Previous studies conducted in our laboratory have determined that the secreted, matricellular protein CCN5 is deficient in human leiomyoma tumors compared to the surrounding myometrium. Further, overexpre... read more
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