Unnatural Sialic Acids for Modulation of Cellular Adhesion and Chimeric Tissue Assembly & Novel Methodologies for Stereocontrolled Deoxy-Sugar Construction

Issa, John.

2017

Description
  • Abstract: I. Synthesis and Expression of Fluorinated Sialic Acids for Modulation of Cellular Adhesion We have demonstrated that by supplementing cell growth media for HeLa and BJAB K20 cells with unnatural sialic acids, we are able to modulate the adherent properties of these cell lines. The cells are able to integrate the unnatural sialic acids onto their surfaces through the sialic acid biosynth... read more
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