The distribution of insertionally polymorphic endogenous retroviruses in breast cancer patients and cancer-free controls.

Wildschutte, Julia H.

Ram, Daniel.

Subramanian, Ravi.

Stevens, Victoria L.

Coffin, John M.

2014

Description
  • Background: Integration of retroviral DNA into a germ cell can result in a provirus that is transmitted vertically to the host's offspring. In humans, such endogenous retroviruses (HERVs) comprise >8% of the genome. The HERV-K(HML-2) proviruses consist of ~90 elements related to mouse mammary tumor virus, which causes breast cancer in mic... read more
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  • Wildschutte, Julia, Daniel Ram, Ravi Subramanian, Victoria L. Stevens, and John M. Coffin. "The distribution of insertionally polymorphic endogenous retroviruses in breast cancer patients and cancer-free controls." Retrovirology 11, no. 1 (12, 2014): 1-13.
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