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First generation Chinese immigrants participating in the large, cross sectional Community Assessment of Freeway Exposure and Health study had an asthma prevalence approximately four times lower than the U.S. born white participants (4.2% versus 17.8%), despite having lower educational attainment and family income. Other differences between Chinese immigrants and U.S. born whites were observed for ... read morecurrent smoker status, proximity to highways, occupational exposure to dust and chemicals, perceived stress, and the level of certain immunological biomarkers. Differences in asthma status were associated with occupational exposure to dust and chemicals, perceived stress, and the presence of certain immunological biomarkers. The difference in asthma prevalence by nationality was considered within the framework of the healthy immigrant theory. The current understanding of genetic, epigenetic, and environmental influences on asthma was also reviewed. Future research directions were highlighted.read less
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