The role of adenomatous polyposis coli and beta-catenin proteins in intellectual disabilities and autism

Alexander, Jonathan.

2017

Description
  • Abstract: Autism spectrum disorders and intellectual disabilities are neurodevelopmental co-morbidities seen in a growing percentage of the population. Large-scale genetic screens of patients with these disorders have revealed that a large proportion of autism causing genes center on key central pathways. One such pathway is the Wnt/β-catenin pathway, with the highest confidence risk gene for ... read more
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