Regulation of Exocyst Function by the Small GTPase RalA.

Hatch, Harold.


  • Abstract: The exocyst is a multisubunit complex that is required for the vesicular trafficking of many proteins. Regulation of exocyst assembly occurs in part through multiple small GTPases, including RalA. Previous work in our lab has shown RalA to be essential for two exocyst dependent processes, delivery of E-Cadherin to the basolateral membrane of H-Ras transformed keratinocytes, and the secre... read more
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