Investigating how postnatal inactivation of Smad proteins in dopaminergic neurons and how neonatal nicotine exposure affects the proper functioning of midbrain dopaminergic neurons and their synaptic projections into the striatum.

Kritzer, Eli C.


  • Midbrain dopaminergic neurons (mDAn) project to the striatum to establish dopaminergic synaptic connections in two distinct pathways: the nigrostriatal and mesolimbic pathways. In the nigrostriatal pathway, mDAn project from the ventral tegmental area (VTA) in the midbrain to the caudate putamen (CPu) in the striatum. In the mesolimbic pathway, mDAn project from the substantia nigra (SNc) in the ... read more
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