Function of STAT3 and SMG1 in maintaining Glioblastoma stem cells.

Sengupta, Sejuti.


  • Abstract: Glioblastoma multiforme (GBM) is the most common and most aggressive tumor of the central nervous system, with a mean survival of only 14 months post diagnosis. Due to the highly lethal nature of glioblastoma, new therapies are urgently needed. It is thought that the major reason for poor prognosis of GBM is that a small population of GBM stem cells (GSC) selectively survives therapy ... read more
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