Interplay between host cell cycle and Legionella pneumophila intracellular replication.

de Jesus-Diaz, Dennise.


  • Abstract: Legionella pneumophila is a Gram-negative, intracellular pathogen that targets amoebal species in aquatic environments and alveolar macrophages during human infections. To sustain intracellular replication L. pneumophila uses a type IV secretion system (T4SS) that translocates bacterial proteins into the host to form the Legionella containing vacuole (LCV), the site of bacterial replicat... read more
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