Mapping the cellular and molecular heterogeneity of normal and malignant breast tissues and cultured cell lines.

Keller, Patricia J.

Lin, Amy F.

Arendt, Lisa M.

Klebba, Ina.

Jones, Ainsley D.

Rudnick, Jenny A.

DiMeo, Theresa A.

Gilmore, Hannah.

Jefferson, Douglas M.

Graham, Roger A.

Naber, Stephen P.

Schnitt, Stuart.

Kuperwasser, Charlotte.

2010

Description
  • Introduction: Normal and neoplastic breast tissues are comprised of heterogeneous populations of epithelial cells exhibiting various degrees of maturation and differentiation. While cultured cell lines have been derived from both normal and malignant tissues, it remains unclear to what extent they retain similar levels of differentiation and heterogeneity as that found within breast tissues.
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  • Keller, Patricia, Amy F. Lin, Lisa M. Arendt, Ina Klebba, Ainsley D. Jones, Jenny A. Rudnick, Theresa A. DiMeo, Hannah Gilmore, Douglas M. Jefferson, Roger A. Graham, Stephen P. Naber, Stuart Schnitt, and Charlotte Kuperwasser. "Mapping the cellular and molecular heterogeneity of normal and malignant breast tissues and cultured cell lines." Breast Cancer Research 12, no. 6 (10, 2010): 1-17.
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05742448z
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