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Abstract: Neural
stimulation is a developing treatment to several disorders. The neural response is
recorded to monitor the patient's response. The field goal is to create an adaptable,
closed-loop system. The stimulation pulse creates an artifact that interferes with the
recording by causing amplifier saturation, making it hard to observe the neural
response. This makes it hard to create a ... read moreclosed-loop system. Means of artifact reduction
are currently researched, none of which are ideal. This thesis examines a layered
approach to artifact rejection, combining techniques: blanking, lowered amplifier gain,
and high dynamic range. This method was tested using a custom circuit board and compared
to a commercially available recording amplifier, to find that the layered approach
recovered to record 2x faster than commercial amplifier. The method was implemented on a
smaller scale using an integrated circuit recording amplifier, with recovery time of
2ms, which is enough time to record the neural
response.
Thesis (M.S.)--Tufts University,
2015.
Submitted to the Dept. of Biomedical
Engineering.
Advisors: Sameer Sonkusale, and Mark
Cronin-Golomb.
Committee: John Lachapelle, Sameer
Sonkusale, and Mark Cronin-Golomb.
Keywords:
Biomedical engineering, and Electrical engineering.read less
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