Function of Plasma Membrane and a3-containing V-ATPases in Breast Cancer.

Cotter, Kristina.


  • Abstract: Metastasis, or the spread of tumor cells from a primary site to secondary sites in the body, is the leading cause of cancer mortality. The development of therapeutics that target key components of this cascade is thus of critical importance. Metastasis requires that cells migrate and invade through extracellular matrix. The vacuolar (H+)-ATPases (V-ATPases) are ubiquitously expressed, AT... read more
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