Role of the neurotrophic receptor TrkC in the pathogenesis of Trypanosoma cruzi infection.

Weinkauf, Craig.


  • Abstract: Chagas' disease is caused by infection with the obligate intracellular parasite Trypanosoma cruzi. Gastrointestinal failure, which results from nerve tissue destruction, is a major complication of Chagas' disease. The neurotrophic receptor TrkA mediates T. cruzi cellular invasion of some neural and non-neural cells, but several infected cell types such as cardiomyocytes and nerve tissue ... read more
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