Elucidating Marginal Zone B cell Fate Decisions using Genome-wide Chromatin Accessibility Profiling

Ahmad, Maimuna S.

Differential chromatin accessibility profiles were seen in mature and precursor marginal zone B cells in the spleen following a Notch-inhibitor treatment. The inhibitor treatment also appeared to deplete the population of both marginal zone B cell types, indicating a role for Notch-signaling in the survival of these cells. Gene expression analysis is required to further elucidate the significance ... read more

This object is in collection:
Undergraduate honors theses
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Tufts University. Department of Biology.
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http://hdl.handle.net/10427/013428
ID: tufts:sd.0000681
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