The Mechanism of Large-Scale CAG Repeat Expansion

Dinter, Teresa
2015

Nearly 30 genetic diseases are caused by the repetition of a short sequence of 2-9 base pairs, known as microsatellites. These microsatellite repeats occur in humans normally; however disease symptoms become apparent once a certain repeat threshold is reached. Usually, these diseases follow a phenomenon known as genetic anticipation, in which each subsequent generation experiences increased diseas... read more

Subjects
Summer Scholars Program.
Tufts University. Department of Biology.
Microsatellites (Genetics)
Genetic disorders.
Permanent URL
http://hdl.handle.net/10427/008317
ID: tufts:sd.0000353
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