The Mechanism of Large-Scale CAG Repeat Expansion.

Dinter, Teresa.
2015

Nearly 30 genetic diseases are caused by the repetition of a short sequence of 2-9 base pairs, known as microsatellites. These microsatellite repeats occur in humans normally; however disease symptoms become apparent once a certain repeat threshold is reached. Usually, these diseases follow a phenomenon known as genetic anticipation, in which each subsequent generation experiences increased diseas... read more

Subjects
Microsatellites (Genetics)
Genetic disorders.
Tufts University. Department of Biology.
Permanent URL
http://hdl.handle.net/10427/008317
ID: tufts:sd.0000353
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