The Role of Chromatin Remodeling Enzymes in Prevention of CAG-Repeat Expansions.

Walsh, Stephen C.

Expansions of CAG repeats, often caused by errors in DNA replication, repair, and recombination, can cause neurodegenerative diseases. However, organisms can employ a number of strategies in preventing genomic instability. Previous data in our lab suggests that acetylation of lysine residues H4-K12 and H4-K16 at CAG repeats is important in marking the DNA for repair, but the exact molecular mech... read more

This object is in collection:
Undergraduate Honors Theses
DNA repair.
Trinucleotide repeats.
Tufts University. Department of Biology.
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