The Role of Chromatin Remodeling Enzymes in Prevention of CAG-Repeat Expansions.

Walsh, Stephen C.
2014

Expansions of CAG repeats, often caused by errors in DNA replication, repair, and recombination, can cause neurodegenerative diseases. However, organisms can employ a number of strategies in preventing genomic instability. Previous data in our lab suggests that acetylation of lysine residues H4-K12 and H4-K16 at CAG repeats is important in marking the DNA for repair, but the exact molecular mech... read more

This object is in collection:
Undergraduate honors theses
Subjects
Chromatin.
DNA repair.
Trinucleotide repeats.
Tufts University. Department of Biology.
Permanent URL
http://hdl.handle.net/10427/000361
ID: tufts:sd.0000190
To Cite: DCA Citation Guide
Usage: Detailed Rights