The Release of Pro-Inflammatory Cytokines Il-6 and Il-8 from HMC-1 Human Mast Cells.Boudreau, Carolyn M.
Abstract: Mast cells are critical in inflammatory processes through their release of pro-inflammatory mediators, including the cytokines IL-6 and IL-8. The aim of this study was to characterize the release of these cytokines from HMC-1 human mast cells. Positive control stimulation of both of these mediators was established through the use of the calcium ionophore A23187 and PMA. It was shown that... read more