Effects of HBP1 Overexpression and EGCG/DAC Treatment on Growth and Metabolism in Triple-Negative Breast Cancer.

Pedro, Brian.

Abstract: The protein HBP1, a transcriptional repressor known to regulate Wnt signaling by preventing expression of Wnt target genes, has been found to be deleted or mutated in clinical invasive breast cancer samples, especially in triple-negative cancers which have increased Wnt signaling. Additionally, decreases in HBP1 have been associated with a shift in carbon metabolism, termed the Warburg e... read more

This object is in collection:
Undergraduate Honors Theses
Breast cancer.
Tufts University. Department of Biology.
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ID: tufts:sd.0000025
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