Osteogenesis Effects Of Growth Factors On An In Vitro Osteogenesis Imperfecta Disease Model.

Brandon, Alissa.

Osteogenesis Imperfecta is a brittle bone disease in which there is an inadequate amount of Bone Collagen protein produced by cells. It has no cure and its treatments are highly ineffective. This project aimed to create a disease model using gene knockdown cells, seeded into a silk scaffold. We attempted to spur bone growth in the model by adding Bone Morphogenic Protein 2 (BMP-2), Transforming G... read more

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Undergraduate Honors Theses
Tufts University. Department of Biomedical Engineering.
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