Establishing ocular cell lines to monitor the ubiquitin-proteasome system (UPS) activity in cells with fluorescent GFP reporters.Bhargava, Pooja.
Background: The Ubiquitin-proteasome system (UPS) plays a critical role in nearly every biological process that includes the removal of undesired damaged proteins. Reduction of UPS capacity is associated with aging and several age-related diseases. In order to understand the relationship between the accumulation of damaged proteins and aging or age-related diseases a reliable experimental system... read more
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- Tufts University. Department of Chemical and Biological Engineering.
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