The effect of the overexpression of DNA polymerase theta in Drosophila melanogaster

Dukhovich, Anna

The purpose of this project was to investigate the effects of upregulation of DNA polymerase theta (Pol ), encoded by the gene mus308, in Drosophila melanogaster. This study was inspired by the recent findings that Pol is upregulated in human breast and other cancers, and that patients with upregulated levels of the protein had poor clinical outcomes. Homologues of DNA Pol exist in h... read more

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Undergraduate Honors Theses
Tufts University. Department of Biology.
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