A System for Detecting Polyglutamine-Encoding Repeat Expansion Events In Mammalian Cells

Gennert, David G.
2012

More than ten human hereditary diseases are known to be caused by the CAGn trinucleotide repeat expansion. The genome of an afflicted individual contains a region of a repeated CAG sequence that has expanded, i.e. increased in repeat number, above a certain threshold. Huntington's disease is one of the best-known CAG expansion diseases, which develops when more than 35 repeats accum... read more

This object is in collection:
Undergraduate honors theses
Subjects
Trinucleotide repeats.
Genetic disorders.
Tufts University. Department of Biology.
Permanent URL
http://hdl.handle.net/10427/77529
ID: tufts:UA005.010.071.00001
To Cite: DCA Citation Guide
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