Differential Gene Expression in a Mouse Model of Huntington's Disease.Carnazza, Kathryn E.
Huntington's disease (HD) is a fatal genetic neurodegenerative disorder. It is inherited in an autosomal dominant fashion. HD typically manifests itself in middle age, though in some cases, symptoms appear earlier. Patients with HD suffer from a gross motor dysfunction, neuronal atrophy, cognitive impairments, psychiatric disturbances, and metabolic disruption, among other symptoms. Death follows ... read more