Extracellular Heat Shock Protein (Hsp)70 and Hsp90alpha Assist in Matrix Metalloproteinase-2 Activation and Breast Cancer Cell Migration and InvasionSims, Jessica D.
Jay, Daniel G.
Breast cancer is second only to lung cancer in cancer-related deaths in women, and the majority of these deaths are caused by metastases. Obtaining a better understanding of migration and invasion, two early steps in metastasis, is critical for the development of treatments that inhibit breast cancer metastasis. In a functional proteomic screen for proteins required for invasion, extracellular hea... read more