Stapled peptides: Magic bullets in nature's arsenal.

Kritzer, Joshua A.
2010.

Selectivity is a key obstacle in drug development. A new study describes how "peptide stapling," a technique for making peptide α-helices more potent and cell permeable, allows the design of MCL-1 inhibitors with extraordinary selectivity.

Subjects
Peptides.
Drug development.
Tufts University. Department of Chemistry.
Permanent URL
http://hdl.handle.net/10427/013729
Original publication
Kritzer, J.A. Stapled peptides: Magic bullets in nature's arsenal. Nat. Chem. Biol. 2010 6(8), 566-567. doi:10.1038/nchembio.407.
ID: tufts:23296
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