On the role of translesion synthesis polymerase Rev1 in homologous recombination and DNA damage tolerance

Khodaverdian, Varandt.
2017

Abstract: DNA is frequently damaged by exogenous and endogenous agents. DNA lesions are particularly dangerous during DNA replication as replicative polymerases associated with the replication fork cannot efficiently utilize modified bases as templates. As a result, the replication fork can stall as it encounters DNA lesions, and ultimately collapse, if the stall persist. Collapsed forks result in... read more

Subjects
Tufts University. Department of Biology.
Permanent URL
http://hdl.handle.net/10427/013621
ID: tufts:23092
To Cite: DCA Citation Guide