Regulation of Interleukin-1β and Tumor Necrosis Factor Secretion from Human Mast Cell

Taracanova, Alexandra.

Abstract: Mast cells are haematopoietically-derived tissue immune cells that participate in allergy, immunity and inflammation through secretion of numerous pro-inflammatory mediators. The peptide substance P (SP) and the cytokines interleukin (IL)-1β and tumor necrosis factor (TNF) have been implicated in inflammatory processes. Here we report that IL-33, a member of the IL-1 family of cytokines,... read more

Sackler School of Graduate Biomedical Sciences. Department of Pharmacology and Experimental Therapeutics.
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ID: tufts:22768
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