Characterization of the mechanisms of HERV-K (HML-2) transcription during human mammary epithelial cell transformation

Montesion, Meagan.

Abstract: Increasing evidence suggests that repetitive elements may play a role in host gene regulation, particularly through the donation of alternative promoters, enhancers, splice sites, and termination signals. Elevated transcript expression of the endogenous retrovirus group HERV-K (HML-2) is seen in many human cancers, although the identity of the individual proviral loci contributing to thi... read more

Sackler School of Graduate Biomedical Sciences. Department of Genetics.
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ID: tufts:22764
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